A new experimental system shows how insulin-producing beta cells react under autoimmune attack during type 1 diabetes; the results could lead to better treatments.
Researchers in the lab of Whitehead Institute Member David Sabatini, identify a key molecule that signals to the cell’s growth-triggering complex mTORC1 when there is sugar to be had, leading to a metabolic response.
Unusual Labmates is a series that explores some of the more unusual models used for research at Whitehead Institute. From rare plants to luminescent beetles to regenerative starfish and worms, these organisms and their unusual traits provide insights into the underlying biology and incredible diversity of living things.
New discoveries about the disruption of condensates in the neurodevelopmental disorder Rett syndrome provide insights into how cells compartmentalize chromosomes as well as new potential paths for therapies.
Elizabeth Boydston is a postdoc in Whitehead Institute Member Sebastian Lourido’s lab investigating the pathogen Toxoplasmsa gondii. We sat down with Boydston to learn more about her and her experiences in and out of the lab.
It's Halloween all year long when you study bat stars. Discover how Whitehead researchers use these brightly-colored creatures to investigate the mysteries of cell division.
Researchers at Whitehead Institute have discovered the master regulator necessary for the pervasive parasite Toxoplasma gondii to chronically infect its host. This finding provides important insights into the parasite’s biology and allows scientists in the laboratory to control if and when the parasite can differentiate into its chronic stage, which may inform research into prevention and treatment of infection.
