Whitehead Institute team finds drugs that activate a key brain gene; initial tests in cells and mice show promise for rare, untreatable neurodevelopmental disorder
Whitehead Institute researchers are uncovering new ways that genes are regulated that upend existing paradigms of gene expression and provide important insights into health and disease. This collection of stories and multimedia explores that research.
Beyond the Gene is a collection of pieces across storytelling mediums--text, audio, and video--that together paint a picture of how current research at Whitehead Institute is expanding the understanding of gene regulation.
Michael Gallagher is a postdoc working jointly in the labs of Whitehead Institute Founding Member Rudolf Jaenisch and Whitehead Institute Member Richard Young investigating gene regulation in neurodegenerative diseases.
In this episode of AudioHelicase, Whitehead Institute Member Ankur Jain discusses how RNA can clump in cells and the diseases, such as Huntington's and amyotrophic lateral sclerosis (ALS), that are associated with these aggregations.